基因名：
ARHGDIA
产品别名：
GDIA1； HEL-S-47e； NPHS8； RHOGDI； RHOGDI-1； ARHGDIA； Rho GDP dissociation inhibitor alpha； Rho GDP dissociation inhibitor alpha； rho GDP-dissociation inhibitor 1； GDP-dissociation inhibitor, aplysia RAS-related 1； Rho GDP dissociation inhibitor (GDI) alpha； epididymis secretory sperm binding protein Li 47e； Rho GDP解离抑制因子α(ARHGDIa)； 磷酸化肿瘤转移抑制基因GDIA1；
背景信息：
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
