重组AICAR甲酰基转移酶蛋白

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重组AICAR甲酰基转移酶蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant ATIC
Recombinant 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase protein

基因名：

ATIC

产品别名：

AICAR； AICARFT； HEL-S-70p； IMPCHASE； PURH； ATIC； 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase； 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase； bifunctional purine biosynthesis protein ATIC； 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase； AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme； AICAR transformylase/inosine monophosphate cyclohydrolase； AICARFT/IMPCHASE； bifunctional purine biosynthesis protein PURH； epididymis secretory sperm binding protein Li 70p； phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase； AICAR甲酰基转移酶；

背景信息：

The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。