基因名：
ATP2A2
产品别名：
ATP2B； DAR； DD； SERCA2； ATP2A2； ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2； ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2； sarcoplasmic/endoplasmic reticulum calcium ATPase 2； ATPase Ca++ transporting cardiac muscle slow twitch 2； ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2； SR Ca(2+)-ATPase 2； calcium pump 2； cardiac Ca2+ ATPase； endoplasmic reticulum class 1/2 Ca(2+) ATPase； 肌浆/内质网钙ATP酶2； 钙离子转运ATP酶A2(ATP2A2)；
背景信息：
ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
