基因名：
BAK1
产品别名：
BAK； BAK-LIKE； BCL2L7； CDN1； BAK1； BCL2 antagonist/killer 1； BCL2 antagonist/killer 1； bcl-2 homologous antagonist/killer； BCL2-like 7 protein； apoptosis regulator BAK； bcl-2-like protein 7； bcl2-L-7； pro-apoptotic protein BAK； Bcl-2同源拮抗剂； Bcl2拮抗/杀伤因子1(BAK1)；
背景信息：
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
