基因名：
BCL6
产品别名：
BCL5； BCL6A； LAZ3； ZBTB27； ZNF51； BCL6； BCL6 transcription repressor； BCL6 transcription repressor； B-cell lymphoma 6 protein； B cell CLL/lymphoma 6； B-cell lymphoma 5 protein； B-cell lymphoma 6 protein transcript； BCL-5； BCL-6； cys-his2 zinc finger transcription factor； lymphoma-associated zinc finger gene on chromosome 3； protein LAZ-3； zinc finger and BTB domain-containing protein 27； zinc finger protein 51； zinc finger transcription factor BCL6S； B-细胞淋巴瘤因子6(Bcl6)； 原癌基因Bcl-6；
背景信息：
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq].
