基因名：
BID
产品别名：
FP497； BID； BH3 interacting domain death agonist； BH3 interacting domain death agonist； BH3-interacting domain death agonist； Human BID coding sequence； apoptic death agonist； desmocollin type 4； p22 BID； BH3相互作用域死亡激动剂(Bid)； BH3结构域凋亡诱导蛋白； 磷酸化BH3结构域凋亡诱导蛋白；
背景信息：
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.
