基因名:
BMP8B
产品别名:
BMP8; OP2; BMP8B; bone morphogenetic protein 8b; bone morphogenetic protein 8b; bone morphogenetic protein 8B; bone morphogenetic protein 8 (osteogenic protein 2); osteogenic protein 2; 骨形态发生蛋白8; 骨形态发生蛋白8b; 骨形成蛋白8B(BMP8B);
背景信息:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008].