基因名：
BMX
产品别名：
ETK； PSCTK2； PSCTK3； BMX； BMX non-receptor tyrosine kinase； BMX non-receptor tyrosine kinase； cytoplasmic tyrosine-protein kinase BMX； BTK-like on X chromosome； Etk/Bmx cytosolic tyrosine kinase； NTK38 tyrosine kinase； bone marrow tyrosine kinase gene in chromosome X protein； epithelial and endothelial tyrosine kinase； BMX非受体酪氨酸激酶(BMX)； 磷酸化非受体性蛋白酪氨酸激酶ETK； 非受体性蛋白酪氨酸激酶ETK；
背景信息：
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
