基因名：
BNIP3
产品别名：
HABON； NIP3； BNIP3； BCL2 interacting protein 3； BCL2 interacting protein 3； BCL2/adenovirus E1B 19 kDa protein-interacting protein 3； BCL2/adenovirus E1B 19kDa interacting protein 3； BCL2/adenovirus E1B interacting protein 3； Hypoxia-Activated BNIP3 Overlapping Non-coding RNA； nineteen kD interacting protein-3； Bcl2/腺病毒E1B相互作用蛋白3(BNIP3)； 促凋亡调节蛋白BNIP3； 磷酸化促凋亡调节蛋白BNIP3；
背景信息：
BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.
