基因名：
BPGM
产品别名：
DPGM； ECYT8； BPGM； bisphosphoglycerate mutase； bisphosphoglycerate mutase； bisphosphoglycerate mutase； 2,3-bisphosphoglycerate mutase, erythrocyte； 2,3-bisphosphoglycerate synthase； 2,3-diphosphoglycerate mutase； BPG-dependent PGAM； erythrocyte 2,3-bisphosphoglycerate mutase； testis secretory sperm-binding protein Li 202a； 二磷酸甘油酸变位酶(BPGM)； 红细胞2,3 -二磷酸甘油酸合成酶；
背景信息：
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
