重组B-Raf原癌基因丝氨酸/苏氨酸蛋白激酶(BRAF)

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重组磷酸化B-Raf蛋白
Recombinant BRAF

基因名：

BRAF

产品别名：

B-RAF1； B-raf； BRAF-1； BRAF1； NS7； RAFB1； BRAF； B-Raf proto-oncogene, serine/threonine kinase； B-Raf proto-oncogene, serine/threonine kinase； serine/threonine-protein kinase B-raf； 94 kDa B-raf protein； B-Raf proto-oncogene serine/threonine-protein kinase (p94)； B-Raf serine/threonine-protein； murine sarcoma viral (v-raf) oncogene homolog B1； proto-oncogene B-Raf； v-raf murine sarcoma viral oncogene homolog B； v-raf murine sarcoma viral oncogene homolog B1； B-Raf原癌基因丝氨酸/苏氨酸蛋白激酶(BRAF)；磷酸化B-Raf；

背景信息：

This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。