基因名：
BSG
产品别名：
5F7； CD147； EMMPRIN； EMPRIN； HAb18G； OK； TCSF； BSG； basigin (Ok blood group)； basigin (Ok blood group)； basigin； OK blood group antigen； collagenase stimulatory factor； extracellular matrix metalloproteinase inducer； hepatoma-associated antigen； leukocyte activation antigen M6； tumor cell-derived collagenase stimulatory factor； 细胞外基质金属蛋白酶诱导因子； 细胞外基质金属蛋白酶诱导因子(CD147)； 细胞外基质金属蛋白酶诱导因子(CD147)真核蛋白；
背景信息：
BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
