基因名：
C1QBP
产品别名：
COXPD33； GC1QBP； HABP1； SF2AP32； SF2p32； gC1Q-R； gC1qR； p32； C1QBP； complement C1q binding protein； complement C1q binding protein； complement component 1 Q subcomponent-binding protein, mitochondrial； ASF/SF2-associated protein p32； C1q globular domain-binding protein； complement component 1, q subcomponent binding protein； glycoprotein gC1qBP； hyaluronan-binding protein 1； mitochondrial matrix protein p32； p33； splicing factor SF2-associated protein； 透明质酸结合蛋白1； 透明质酸结合蛋白1(C1QBP)；
背景信息：
Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
