基因名：
C3
产品别名：
AHUS5； ARMD9； ASP； C3a； C3b； CPAMD1； HEL-S-62p； C3； complement C3； complement C3； complement C3； C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1； C3a anaphylatoxin； acylation-stimulating protein cleavage product； complement component 3； complement component C3a； complement component C3b； epididymis secretory sperm binding protein Li 62p； prepro-C3； 补体C3b； 补体C3b-α链； 补体C3cα链片段1； 补体C3dg片段； 补体C3d片段； 补体C3d片段蛋白； 补体C3g片段； 补体成分3(C3)； 补体成分3a(C3a)； 补体成分3a(C3a)真核蛋白； 补体片段C3c； 过敏毒素C3/补体C3； 过敏毒素C3（补体C3）；
背景信息：
Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.
