基因名：
CALR
产品别名：
CRT； HEL-S-99n； RO； SSA； cC1qR； CALR； calreticulin； calreticulin； calreticulin； CRP55； ERp60； HACBP； Sicca syndrome antigen A (autoantigen Ro; calreticulin)； calregulin； endoplasmic reticulum resident protein 60； epididymis secretory sperm binding protein Li 99n； grp60； 钙网蛋白； 钙网蛋白(CALR)； 钙网蛋白(CALR)真核蛋白；
背景信息：
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
