基因名：
CAMK2A
产品别名：
CAMKA； CaMKIINalpha； CaMKIIalpha； MRD53； MRT63； CAMK2A； calcium/calmodulin dependent protein kinase II alpha； calcium/calmodulin dependent protein kinase II alpha； calcium/calmodulin-dependent protein kinase type II subunit alpha； CaM kinase II alpha subunit； CaM-kinase II alpha chain； CaMK-II alpha subunit； caM kinase II subunit alpha； caMK-II subunit alpha； calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha； calcium/calmodulin-dependent protein kinase II alpha-B subunit； calcium/calmodulin-dependent protein kinase type II alpha chain； 磷酸化钙/钙调素依赖蛋白激酶2α； 钙/钙调素依赖蛋白激酶2b/2γ； 钙/钙调素依赖蛋白激酶2α； 钙/钙调蛋白依赖性蛋白激酶Ⅱα(CAMK2a)；
背景信息：
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008].
