基因名：
CASP2
产品别名：
CASP-2； ICH1； NEDD-2； NEDD2； PPP1R57； CASP2； caspase 2； caspase 2； caspase-2； caspase 2 apoptosis-related cysteine peptidase； neural precursor cell expressed developmentally down-regulated protein 2； protease ICH-1； protein phosphatase 1, regulatory subunit 57； 半胱胺酸蛋白酶-2； 活化半胱胺酸蛋白酶蛋白-2； 胱天蛋白酶2(CASP2)；
背景信息：
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
