基因名:
CASP6
产品别名:
CSP-6; MCH2; CASP6; caspase 6; caspase 6; caspase-6; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; 半胱胺酸蛋白酶蛋白-6; 半胱胺酸蛋白酶蛋白-6前体蛋白; 磷酸化半胱胺酸蛋白酶蛋白6; 胱天蛋白酶6(CASP6);
背景信息:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]