基因名：
CD47
产品别名：
IAP； MER6； OA3； CD47； CD47 molecule； CD47 molecule； leukocyte surface antigen CD47； CD47 antigen (Rh-related antigen, integrin-associated signal transducer)； CD47 glycoprotein； Rh-related antigen； antigen identified by monoclonal antibody 1D8； antigenic surface determinant protein OA3； integrin associated protein； integrin-associated signal transducer； CD47蛋白； 整合素关联蛋白(IAP)； 整合素相关蛋白CD47； 整合素相关蛋白CD47+O11697； 整合素相关蛋白CD47+O14153；
背景信息：
CD47(Integrin-Associated Protein,IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
