基因名:
CDH11
产品别名:
CAD11; CDHOB; ESWS; OB; OSF-4; TBHS2; CDH11; cadherin 11; cadherin 11; cadherin-11; cadherin 11, type 2, OB-cadherin (osteoblast); 造骨细胞钙黏蛋白(CDHOB); 钙粘附蛋白-11;
背景信息:
The cadherins are a family of Ca++-dependent adhesion molecules that influence cell-cell binding and are critical to the maintenance of tissue structure and morphogenesis. OB-cadherin (osteoblast-cadherin, cadherin-11, OSF-4) has two forms, OB-cadherin-1 and OB-cadherin-2. OB-cadherin-2 has a truncated cytoplasmic domain, missing amino acids 694-796. Both OB-cadherins are expressed in osteoblastic cell lines with low expression seen in lungs, testis and brain.