基因名:
CDH17
产品别名:
CDH16; HPT-1; HPT1; CDH17; cadherin 17; cadherin 17; cadherin-17; HPT-1 cadherin; LI cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; liver-intestine cadherin; 肝肠钙粘连蛋白; 肝肠钙黏蛋白(CDH17);
背景信息:
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.