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重组周期素依赖性激酶抑制因子2B(CDKN2B)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组细胞周期蛋白依赖性激酶抑制剂2B
Recombinant CDKN2B
基因名:

CDKN2B


产品别名:

CDK4I; INK4B; MTS2; P15; TP15; p15INK4b; CDKN2B; cyclin dependent kinase inhibitor 2B; cyclin dependent kinase inhibitor 2B; cyclin-dependent kinase 4 inhibitor B; CDK inhibitory protein; CDK4B inhibitor; MTS-2; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinases 4 and 6 binding protein; multiple tumor suppressor 2; p14-INK4b; p14_CDK inhibitor; p14_INK4B; p15 CDK inhibitor; p15-INK4b; p15_INK4B; 周期素依赖性激酶抑制因子2B(CDKN2B); 细胞周期蛋白依赖性激酶抑制剂2B;


背景信息:
p15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.
 
 
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