基因名：
CDKN2C
产品别名：
INK4C； p18； p18-INK4C； CDKN2C； cyclin dependent kinase inhibitor 2C； cyclin dependent kinase inhibitor 2C； cyclin-dependent kinase 4 inhibitor C； CDK6 inhibitor p18； cyclin-dependent inhibitor； cyclin-dependent kinase 6 inhibitor p18； cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)； p18-INK6； 细胞周期蛋白依赖性激酶抑制剂2C；
背景信息：
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.
