基因名:
CEBPA
产品别名:
C/EBP-alpha; CEBP; CEBPA; CCAAT enhancer binding protein alpha; CCAAT enhancer binding protein alpha; CCAAT/enhancer-binding protein alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT增强子结合蛋白α(CEBPa); 磷酸化转录调节因子CEBPα; 转录调节因子C/EBPα;
背景信息:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq, Jul 2008].