基因名:
CEBPB
产品别名:
C/EBP-beta; IL6DBP; NF-IL6; TCF5; CEBPB; CCAAT enhancer binding protein beta; CCAAT enhancer binding protein beta; CCAAT/enhancer-binding protein beta; CCAAT/enhancer binding protein (C/EBP), beta; interleukin 6-dependent DNA-binding protein; nuclear factor NF-IL6; nuclear factor of interleukin 6; transcription factor 5; transcription factor C/EBP beta; CCAAT增强子结合蛋白β(CEBPb); 磷酸化转录调节因子CEBPβ; 转录调节因子C/EBPβ;
背景信息:
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq].