基因名：
CHD3
产品别名：
Mi-2a； Mi2-ALPHA； SNIBCPS； ZFH； CHD3； chromodomain helicase DNA binding protein 3； chromodomain helicase DNA binding protein 3； chromodomain-helicase-DNA-binding protein 3； ATP-dependent helicase CHD3； CHD-3； hZFH； mi-2 autoantigen 240 kDa protein； zinc finger helicase； zinc-finger helicase (Snf2-like)； ATP依赖的解旋酶CHD3； 染色质域解旋酶DNA结合蛋白3(CHD3)； 染色质解旋酶DNA结合蛋白3；
背景信息：
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
