基因名:
CHN1
产品别名:
ARHGAP2; CHN; DURS2; NC; RHOGAP2; CHN1; chimerin 1; chimerin 1; N-chimaerin; A-chimaerin; Rho GTPase-activating protein 2; a2-chimaerin; alpha-chimerin; chimaerin 1; chimerin (chimaerin) 1; n-chimerin; α1-chimaerin蛋白; 嵌合蛋白1(CHN1);
背景信息:
This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]