基因名：
CHRNA5
产品别名：
LNCR2； CHRNA5； cholinergic receptor nicotinic alpha 5 subunit； cholinergic receptor nicotinic alpha 5 subunit； neuronal acetylcholine receptor subunit alpha-5； Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5； acetylcholine receptor, nicotinic, alpha 5 (neuronal)； cholinergic receptor, nicotinic alpha 5； cholinergic receptor, nicotinic, alpha 5 (neuronal)； neuronal nicotinic acetylcholine receptor, alpha5 subunit； 烟碱型乙酰胆碱受体α5； 烟碱型胆碱受体α5(CHRNa5)；
背景信息：
Neuronal Acetylcholine Receptor Subunit α-5 (NACHRA5) is a member of the ligand-gated ion channel family. Neuronal AChR is composed of two different type of subunits: α and non-α. When NACHRA5 binds to acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits, leading to the opening of an ion-conducting channel across the plasma membrane. Genetic variations in NACHRA5 have been related to susceptibility to smoking-related behavioral traits and lung cancer, contributing to the smoking quantitative trait locus 3.
