基因名：
AP2M1
产品别名：
AP50； CLAPM1； MRD60； mu2； AP2M1； adaptor related protein complex 2 subunit mu 1； adaptor related protein complex 2 subunit mu 1； AP-2 complex subunit mu； AP-2 mu 2 chain； HA2 50 kDA subunit； adaptin-mu2； adaptor protein complex AP-2 subunit mu； adaptor related protein complex 2 mu 1 subunit； adaptor-related protein complex 2 subunit mu； clathrin adaptor complex AP2, mu subunit； clathrin assembly protein complex 2 medium chain； clathrin assembly protein complex 2 mu medium chain； clathrin coat adaptor protein AP50； clathrin coat assembly protein AP50； clathrin coat-associated protein AP50； clathrin-associated/assembly/adaptor protein, medium 1； plasma membrane adaptor AP-2 50 kDa protein； plasma membrane adaptor AP-2 50kDA protein； 接头相关蛋白复合体AP-2μ链1； 磷酸化接头相关蛋白复合体AP-2μ链1； 衔接因子相关蛋白复合体2μ1(AP2m1)；
背景信息：
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
