基因名:
CPB1
产品别名:
CPB; PASP; PCPB; CPB1; carboxypeptidase B1; carboxypeptidase B1; carboxypeptidase B; carboxypeptidase B1 (tissue); pancreas-specific protein; pancreatic carboxypeptidase B; procarboxypeptidase B; protaminase; tissue carboxypeptidase B; 羧肽酶B1(CPB1); 胰羧肽酶B1;
背景信息:
Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.