基因名:
ATF6B
产品别名:
CREB-RP; CREBL1; G13; ATF6B; activating transcription factor 6 beta; activating transcription factor 6 beta; cyclic AMP-dependent transcription factor ATF-6 beta; Creb-related protein; cAMP response element-binding protein-related protein; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; protein G13; 活化转录因子6β;
背景信息:
ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6beta homodimer or an ATF-6Alpha/beta heterodimer. Binding of the ATF-6beta homodimer or ATF-6Alpha/beta heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.