基因名：
CREM
产品别名：
CREM-2； ICER； hCREM-2； CREM； cAMP responsive element modulator； cAMP responsive element modulator； cAMP-responsive element modulator； CREM 2alpha-b protein； CREM 2beta-a protein； cAMP response element modulator； inducible cAMP early repressor ICER； cAMP应答元件调节因子(CREM)； 环磷酸腺苷反应元件调节蛋白； 磷酸化环磷酸腺苷反应元件调节蛋白；
背景信息：
CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator.
