基因名:
CRKL
产品别名:
CRKL; CRK like proto-oncogene, adaptor protein; CRK like proto-oncogene, adaptor protein; crk-like protein; v-crk avian sarcoma virus CT10 oncogene homolog-like; Crk样蛋白(CRKL); 接头蛋白CrkL; 磷酸化接头蛋白CrkL;
背景信息:
Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential.