基因名：
CRYAB
产品别名：
CMD1II； CRYA2； CTPP2； CTRCT16； HEL-S-101； HSPB5； MFM2； CRYAB； crystallin alpha B； crystallin alpha B； alpha-crystallin B chain； epididymis secretory protein Li 101； heat shock protein beta-5； heat-shock 20 kD like-protein； renal carcinoma antigen NY-REN-27； rosenthal fiber component； α晶状体球蛋白B/αB-crystallin； 晶状体蛋白αB(CRYaB)； 磷酸化α晶状体球蛋白B/αB-crystallin； 磷酸化热休克蛋白β5/αb晶体蛋白质/α-晶体蛋白b链； 磷酸化热休克蛋白β5/α晶状体球蛋白B/αB-crystallin；
背景信息：
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).
