基因名:
CTBP2
产品别名:
CTBP2; C-terminal binding protein 2; C-terminal binding protein 2; C-terminal-binding protein 2; ribeye; C末端结合蛋白2; 羧基端结合蛋白2(CTBP2);
背景信息:
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2014].