基因名:
CTNND1
产品别名:
BCDS2; CAS; CTNND; P120CAS; P120CTN; p120; p120(CAS); p120(CTN); CTNND1; catenin delta 1; catenin delta 1; catenin delta-1; cadherin-associated Src substrate; catenin (cadherin-associated protein), delta 1; p120 catenin; δ连环蛋白; 磷酸化δ连环蛋白; 连环蛋白δ1(CTNNd1); 连环蛋白δ1(CTNNd1)真核蛋白;
背景信息:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.