基因名：
CYP2C9
产品别名：
CPC9； CYP2C； CYP2C10； CYPIIC9； P450-2C9； P450IIC9； CYP2C9； cytochrome P450 family 2 subfamily C member 9； cytochrome P450 family 2 subfamily C member 9； cytochrome P450 2C9； cytochrome P-450 S-mephenytoin 4-hydroxylase； cytochrome P-450MP； cytochrome P450 PB-1； cytochrome P450, family 2, subfamily C, polypeptide 9； flavoprotein-linked monooxygenase； microsomal monooxygenase； xenobiotic monooxygenase； 细胞色素P450 2C9； 细胞色素P450家族成员2C9(CYP2C9)；
背景信息：
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
