重组细胞色素C P450 17A1蛋白

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重组细胞色素C P450 17A1蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组细胞色素P450 17蛋白
Recombinant CYP17A1

基因名：

CYP17A1

产品别名：

CPT7； CYP17； P450C17； S17AH； CYP17A1； cytochrome P450 family 17 subfamily A member 1； cytochrome P450 family 17 subfamily A member 1； steroid 17-alpha-hydroxylase/17,20 lyase； 17-alpha-hydroxyprogesterone aldolase； CYPXVII； cytochrome P450 17A1； cytochrome P450, family 17, subfamily A, polypeptide 1； cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia； cytochrome P450-C17； cytochrome P450c17； cytochrome p450 XVIIA1； steroid 17-alpha-monooxygenase；细胞色素C P450 17A1；细胞色素P450 17；细胞色素P450 17A1(CYP17A1)；

背景信息：

Cytochrome P450 17A1 (CYP17A1) belongs to the cytochrome P450 family; it plays a role in the conversion of pregnenolone and progesterone into their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. CYP17A1 also catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. CYP17A1 is involved in sexual development during fetal life and at puberty. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5). AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol.