基因名：
DAD1
产品别名：
OST2； DAD1； defender against cell death 1； defender against cell death 1； dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1； DAD-1； oligosaccharyl transferase subunit DAD1； oligosaccharyltransferase 2 homolog； oligosaccharyltransferase subunit 2 (non-catalytic)； 细胞死亡防卫蛋白1；
背景信息：
Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
