基因名：
DDX5
产品别名：
G17P1； HLR1； HUMP68； p68； DDX5； DEAD-box helicase 5； DEAD-box helicase 5； probable ATP-dependent RNA helicase DDX5； ATP-dependent RNA helicase DDX5； DEAD (Asp-Glu-Ala-Asp) box helicase 5； DEAD (Asp-Glu-Ala-Asp) box polypeptide 5； DEAD box protein 5； DEAD box-5； DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)； RNA helicase p68； DEAD框肽5(DDX5)； 三磷酸腺苷依赖解旋酶ddx5； 磷酸化三磷酸腺苷依赖解旋酶ddx5；
背景信息：
p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.
