基因名:
DIO2
产品别名:
5DII; D2; DIOII; SELENOY; SelY; TXDI2; DIO2; iodothyronine deiodinase 2; iodothyronine deiodinase 2; type II iodothyronine deiodinase; deiodinase, iodothyronine type II; deiodinase-2; deiodonase-2; selenoprotein Y; thyroxine deiodinase, type II; type 2 DI; type 2 iodothyronine deiodinase; type-II 5'-deiodinase; type-II 5'deiodinase; 碘甲腺原氨酸脱碘酶Ⅱ(DIO2); 脱碘酶2;
背景信息:
DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.