基因名：
DLD
产品别名：
DLDD； DLDH； E3； GCSL； LAD； OGDC-E3； PHE3； DLD； dihydrolipoamide dehydrogenase； dihydrolipoamide dehydrogenase； dihydrolipoyl dehydrogenase, mitochondrial； E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex； diaphorase； epididymis secretory sperm binding protein； glycine cleavage system L protein； glycine cleavage system protein L； lipoamide dehydrogenase； lipoamide reductase； lipoyl dehydrogenase； 二氢硫辛酸脱氢酶(DLD)； 硫辛酰胺脱氢酶；
背景信息：
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
