基因名：
DOCK1
产品别名：
DOCK180； ced5； DOCK1； dedicator of cytokinesis 1； dedicator of cytokinesis 1； dedicator of cytokinesis protein 1； 180 kDa protein downstream of CRK； DOwnstream of CrK； 细胞质分裂付出蛋白1； 胞质分裂作用因子1(DOCK1)；
背景信息：
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.
Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
