基因名:
DRD3
产品别名:
D3DR; ETM1; FET1; DRD3; dopamine receptor D3; dopamine receptor D3; D(3) dopamine receptor; essential tremor 1; 多巴胺受体D3; 多巴胺受体D3(DRD3);
背景信息:
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is expressed in phylogenetically older regions of the brain, suggesting that it plays a role in cognitive and emotional functions. It is a target for drugs which treat schizophrenia, drug addiction, and Parkinson disease. Alternative splicing of this gene results in multiple transcript variants that would encode different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). Also known as: dopamine D3 receptor; 3 dopamine receptor; D; Dopamine receptor D3; DRD; ETM1; FET1.