基因名：
DSG1
产品别名：
CDHF4； DG1； DSG； EPKHE； EPKHIA； PPKS1； SPPK1； DSG1； desmoglein 1； desmoglein 1； desmoglein-1； cadherin family member 4； desmosomal glycoprotein 1； pemphigus foliaceus antigen； 桥粒芯糖蛋白1； 桥粒芯糖蛋白1(DSG1)；
背景信息：
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
