基因名:
DSPP
产品别名:
DFNA39; DGI1; DMP3; DPP; DSP; DSPP; dentin sialophosphoprotein; dentin sialophosphoprotein; dentin sialophosphoprotein; deafness, autosomal dominant 39; dentin phosphophoryn; dentin phosphoprotein; dentin phosphoryn; dentin sialoprotein; 牙本质涎磷蛋白(DSPP); 牙本质磷蛋白; 牙本质磷蛋白/牙本质骨唾液酸糖蛋白/牙本质骨唾液酸磷蛋白;
背景信息:
This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jul 2008]