基因名：
EDNRB
产品别名：
ABCDS； ET-B； ET-BR； ETB； ETB1； ETBR； ETRB； HSCR； HSCR2； WS4A； EDNRB； endothelin receptor type B； endothelin receptor type B； endothelin receptor type B； Hirschsprung disease 2； endothelin receptor non-selective type； endothelin receptor subtype B1； 内皮素B受体； 内皮素受体B(ETRB)；
背景信息：
Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding - suggesting that these two variants are functionally distinct.
