基因名：
EIF4G2
产品别名：
AAG1； DAP5； NAT1； P97； EIF4G2； eukaryotic translation initiation factor 4 gamma 2； eukaryotic translation initiation factor 4 gamma 2； eukaryotic translation initiation factor 4 gamma 2； DAP-5； aging-associated protein 1； death-associated protein 5； eIF-4-gamma 2； eIF-4G 2； eIF4G 2； eukaryotic translation initiation factor 4G-like 1； 死亡相关蛋白5；
背景信息：
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
