基因名:
ELK1
产品别名:
ELK1; ETS transcription factor ELK1; ETS transcription factor ELK1; ETS domain-containing protein Elk-1; ELK1, ETS transcription factor; ELK1, member of ETS oncogene family; ETS-like gene 1; tyrosine kinase (ELK1) oncogene; 磷酸化细胞转录因子ELK1; 细胞转录因子ELK1;
背景信息:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].