基因名:
FBL
产品别名:
FIB; FLRN; Nop1; RNU3IP1; FBL; fibrillarin; fibrillarin; rRNA 2'-O-methyltransferase fibrillarin; 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; RNA, U3 small nucleolar interacting protein 1; U6 snRNA 2'-O-methyltransferase fibrillarin; histone-glutamine methyltransferase; 核仁纤维蛋白; 纤维蛋白(FBL);
背景信息:
Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.